Anti-WNK1 monoclonal antibody (DCABH-6070) Knockout Validated

Rabbit anti-Human WNK1 monoclonal antibody for WB, ICC/IF, FC

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Clone
FQS3854(4)
Species Reactivity
Human
Immunogen
Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human WNK1 aa 100-200 (Cysteine residue). The exact sequence is proprietary.Database link: Q9H4A3
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/1000 - 1/10000; ICC/IF: 1/100 - 1/250; Flow Cyt: 1/100 - 1/500.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
WNK1; WNK lysine deficient protein kinase 1; hereditary sensory neuropathy, type II , HSN2, PRKWNK1, protein kinase, lysine deficient 1; serine/threonine-protein kinase WNK1; HSAN2; erythrocyte 65 kDa protein
Entrez Gene ID
UniProt ID

Product Background


Pathway
EGFR1 Signaling Pathway, organism-specific biosystem;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Choate, KA; Kahle, KT; et al. WNK1, a kinase mutated in inherited hypertension with hyperkalemia, localizes to diverse Cl- - transporting epithelia. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 100:663-668(2003).
Vitari, AC; Deak, M; et al. WNK1, the kinase mutated in an inherited high-blood-pressure syndrome, is a novel PKB (protein kinase B)/Akt substrate. BIOCHEMICAL JOURNAL 378:257-268(2004).

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