Anti-WNK1 monoclonal antibody (DMAB36341)

Rabbit anti-Human WNK1 monoclonal antibody for WB, IHC Datasheet

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Specifications


Host Species
Rabbit
Clone
FQS3837
Species Reactivity
Human
Conjugate
Unconjugated

Applications


Application Notes
WB: 1:1,000 - 10,000; IHC: 1:50 - 100
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
WNK1; WNK lysine deficient protein kinase 1; hereditary sensory neuropathy, type II , HSN2, PRKWNK1, protein kinase, lysine deficient 1; serine/threonine-protein kinase WNK1; HSAN2; erythrocyte 65 kDa protein
Entrez Gene ID
UniProt ID

Product Background


Pathway
EGFR1 Signaling Pathway, organism-specific biosystem;

Citations


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References


Jiang, ZY; Zhou, QL; et al. Identification of WNK1 as a substrate of Akt/protein kinase B and a negative regulator of insulin-stimulated mitogenesis in 3T3-L1 cells. JOURNAL OF BIOLOGICAL CHEMISTRY 280:21622-21628(2005).
Vitari, AC; Deak, M; et al. WNK1, the kinase mutated in an inherited high-blood-pressure syndrome, is a novel PKB (protein kinase B)/Akt substrate. BIOCHEMICAL JOURNAL 378:257-268(2004).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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