Specifications
Species Reactivity
Mouse; Rat; Human
Immunogen
Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human WDR1 aa 300-400. The exact sequence is proprietary.Database link: O75083
Applications
Application Notes
WB: 1/1000 - 1/10000; IHC-P: 1/50 - 1/100; ICC/IF: 1/50 - 1/100;
Target
Alternative Names
WDR1; WD repeat domain 1; WD repeat-containing protein 1; actin-interacting protein 1; AIP1; NORI-1;
Product Background
Antigen Description
This gene encodes a protein containing 9 WD repeats. WD repeats are approximately 30- to 40-amino acid domains containing several conserved residues, mostly including a trp-asp at the C-terminal end. WD domains are involved in protein-protein interactions. The encoded protein may help induce the disassembly of actin filaments. Two transcript variants encoding different isoforms have been found for this gene.
Pathway
Hemostasis, organism-specific biosystem; Hypertrophy Model, organism-specific biosystem; Platelet activation, signaling and aggregation, organism-specific biosystem; Platelet degranulation, organism-specific biosystem; Response to elevated platelet cytosolic Ca2+, organism-specific biosystem;
Citations
Publication ()
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COA
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