A synthetic peptide of human VPS24 is used for rabbit immunization.
Conjugate
Unconjugated
Target
Alternative Names
CHMP3; charged multivesicular body protein 3; NEDF; VPS24; CGI-149; 25.1 protein; CHMP family, member 3; chromatin-modifying protein 3; vacuolar protein sorting 24 homolog; neuroendocrine differentiation factor; vacuolar protein sorting-associated protein
This gene encodes a protein that sorts transmembrane proteins into lysosomes/vacuoles via the multivesicular body (MVB) pathway. This protein, along with other soluble coiled-coil containing proteins, forms part of the ESCRT-III protein complex that binds to the endosomal membrane and recruits additional cofactors for protein sorting into the MVB. This protein may also co-immunoprecipitate with a member of the IFG-binding protein superfamily. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ring finger protein 103 (RNF103) gene.
Pathway
Budding and maturation of HIV virion; Disease; ESCRT-III complex; ESCRT-III complex; Endocytosis; Endocytosis; Endosomal Sorting Complex Required For Transport (ESCRT); HIV Infection; HIV Life Cycle; Internalization of ErbB1; Late Phase of HIV Life Cycle;
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
Citations
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Nakamori, M; Takahashi, T; et al. Cyclin-dependent kinase 5 immunoreactivity for granulovacuolar degeneration. NEUROREPORT 23:867-872(2012).
Schulz, C; Leuschen, NV; et al. Identification of novel downstream targets of platelet glycoprotein VI activation by differential proteome analysis: implications for thrombus formation. BLOOD 115:4102-4110(2010).
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COA
Certificate of Analysis
