Synthetic peptide corresponding to a region within amino acids 1 and 44 of USP14.
Conjugate
Unconjugated
Applications
Application Notes
WB: 1:500-1:3000
General Notes
This product (Catalog No. DPABH-00457) is a rabbit-derived IgG polyclonal antibody raised against human USP14, targeting the amino acid region 1–44 of the protein. It has been affinity purified by protein A. This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. Mice with a mutation that results in reduced expression of the ortholog of this protein are retarded for growth, develop severe tremors by 2 to 3 weeks of age followed by hindlimb paralysis and death by 6 to 10 weeks of age. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. DPABH-00457 is suitable for use in Western blot (WB) (1:500–1:3,000) application. DPABH-00457 is supplied as a liquid formulation in 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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