General Notes
This product (Catalog No. DPABH-05316) is a rabbit-derived polyclonal antibody raised against human UMPS, targeting the amino acid region 226–480 of the protein. It has been affinity purified by Protein A. Uridine 5'-monophosphate synthase (UMPS) is a critical bifunctional enzyme in humans that catalyzes the final two steps of de novo pyrimidine biosynthesis, converting orotate into uridine monophosphate (UMP). It combines orotate phosphoribosyltransferase (OPRT) and orotidine-5'-phosphate decarboxylase (ODC) activities, crucial for RNA/DNA synthesis. Deficiencies cause hereditary orotic aciduria, a rare metabolic disorder.
DPABH-05316 is suitable for use in ELISA (1:4,000–1:8,000), IHC (1:50–1:100), Western blot (WB) (1:1,000–1:4,000) applications.
DPABH-05316 is supplied as a liquid formulation in 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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