Anti-UCHL1 (aa 101-190) polyclonal antibody

Species Reactivity

Human; Rat

Immunogen

UCHL1 (NP_004172, 101 a.a. ~ 190 a.a) partial recombinant protein with GST tag. The sequence is NNQDKLGFEDGSVLKQFLSETEKMSPEDRAKCFEKNEAIQAAHDAVAQEGQCRVDDKVNF HFILFNNVDGHLYELDGRMPFPVNHGASSE

Conjugate

Alternative Names

UCHL1; ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase); NDGOA; PARK5; PGP95; PGP9.5; Uch-L1; HEL-117; PGP 9.5; ubiquitin carboxyl-terminal hydrolase isozyme L1; ubiquitin thioesterase L1; epididymis luminal protein 117; neuron cytoplasmi

Entrez Gene ID

UniProt ID

Antigen Description

The protein encoded by this gene belongs to the peptidase C12 family. This enzyme is a thiol protease that hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. This gene is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. Mutations in this gene may be associated with Parkinson disease.[provided by RefSeq, Sep 2009]

Pathway

Alpha-synuclein signaling; Parkinsons Disease Pathway;