Anti-UCHL1 Polyclonal Antibody (CABT-L2205) Knockout Validated

Rabbit Anti-Human UCHL1 (Gln2~Ala223) Polyclonal Antibody for WB

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human, Rat
Immunogen
Recombinant fragment corresponding to human UCHL1 (Gln2~Ala223)
Conjugate
Unconjugated

Applications


Application Notes
Recommended dilution: WB: 0.5-2 ug/ml; 1:250-1000
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Data Examples


Knockout Varification: Lane 1: Wild-type A549 cell lysate. Lane 2: UCHL1 knockout A549 cell lysate. Predicted MW: 25kd, Observed MW: 26kd
Western Blot. Sample. Human A549 cell lysate.
Western Blot. Sample. Rat Cerebrum lysate.
Western Blot. Sample. Rat Spinal cord lysate.
Western Blot. Sample. Rat Testis lysate.

Target


Alternative Names
PARK5; PGP9.5; Uch-L1; Neuron cytoplasmic protein 9.5; Ubiquitin thioesterase L1; Ubiquitin carboxyl-terminal hydrolase isozyme L1
Entrez Gene ID
UniProt ID

Product Background


Pathway
Alpha-synuclein signaling; Parkinsons disease; Parkinsons Disease Pathway; Proteasome Degradation;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


El-Mallawany, NK; Day, N; et al. Differential proteomic analysis of endemic and sporadic Epstein-Barr virus-positive and negative Burkitt lymphoma. EUROPEAN JOURNAL OF CANCER 51:92-100(2015).
Liu, Y; Chen, YY; et al. Association between ubiquitin carboxy-terminal hydrolase-L1 S18Y variant and risk of Parkinson's disease: the impact of ethnicity and onset age. NEUROLOGICAL SCIENCES 36:179-188(2015).

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