Specifications
Species Reactivity
Mouse; Human
Immunogen
A synthetic peptide corresponding to residues near the N-terminus of human UBF1
Applications
Application Notes
WB: 1/500; IHC-P: 1/100 - 1/250; ICC: 1/100 - 1/250; Flow Cyt: 1/30 - 1/50;
Target
Alternative Names
UBTF; upstream binding transcription factor, RNA polymerase I; nucleolar transcription factor 1; NOR 90; UBF; autoantigen NOR-90; 90-kDa nucleolus organizer region autoantigen; UBF1; UBF-1; NOR-90;
Product Background
Antigen Description
Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream control element.
Pathway
Gene Expression, organism-specific biosystem; RNA Polymerase I Chain Elongation, organism-specific biosystem; RNA Polymerase I Promoter Clearance, organism-specific biosystem; RNA Polymerase I Promoter Escape, organism-specific biosystem; RNA Polymerase I Promoter Opening, organism-specific biosystem; RNA Polymerase I Transcription, organism-specific biosystem; RNA Polymerase I Transcription Initiation, organism-specific biosystem;
Citations
Publication ()
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COA
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