Anti-UBQLN2 monoclonal antibody (CAB-5011MH)

Mouse anti-UBQLN2 monoclonal antibody for ELISA, WB, IF Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG2a
Clone
6G6
Species Reactivity
Human
Immunogen
UBQLN2 (NP_038472, 555 a.a. ~ 625 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Unconjugated

Applications


Application Notes
WB: 1:500-1000
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
UBQLN2; ubiquilin 2; ubiquilin-2; Chap1; CHAP1/DSK2; Dsk2
Entrez Gene ID
UniProt ID

Product Background


Pathway
Protein processing in endoplasmic reticulum, organism-specific biosystem; Protein processing in endoplasmic reticulum, conserved biosystem;

Citations


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References


Fahed, AC; McDonough, B; et al. UBQLN2 Mutation Causing Heterogeneous X-Linked Dominant Neurodegeneration. ANNALS OF NEUROLOGY 75:793-798(2014).
Xia, YX; Yan, LH; et al. Pathogenic mutation of UBQLN2 impairs its interaction with UBXD8 and disrupts endoplasmic reticulum-associated protein degradation. JOURNAL OF NEUROCHEMISTRY 129:99-106(2014).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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