Specifications
Species Reactivity
Mouse; Human
Immunogen
Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human Tyrosinase Related Protein 75 aa 50-150 (Cysteine residue). The exact sequence is proprietary.Database link: P17643
Applications
Application Notes
IHC-P: 1/100 - 1/250; WB: 1/10000 - 1/50000; ICC/IF: 1/100 - 1/250.
Target
Alternative Names
TYRP1; tyrosinase-related protein 1; CAS2, TYRP; 5,6-dihydroxyindole-2-carboxylic acid oxidase; b PROTEIN; CATB; GP75; TRP; TRP1; TRP-1; catalase B; DHICA oxidase; glycoprotein 75; melanoma antigen gp75; CAS2; TYRP; b-PROTEIN;
Product Background
Antigen Description
Oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6-quinone-2-carboxylic acid. May regulate or influence the type of melanin synthesized.
Pathway
Direct p53 effectors, organism-specific biosystem; Melanogenesis, organism-specific biosystem; Melanogenesis, conserved biosystem; Metabolic pathways, organism-specific biosystem; Tyrosine metabolism, organism-specific biosystem; Tyrosine metabolism, conserved biosystem; ethanol degradation IV, organism-specific biosystem;
Citations
Publication ()
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