TWIST1 (NP_000465, 100 a.a. ~ 202 a.a) partial recombinant protein with GST tag. The sequence is PQSYEELQTQRVMANVRERQRTQSLNEAFAALRKIIPTLPSDKLSKIQTLKLAARYIDFL YQVLQSDELDSKMASCSYVAHERLSYAFSVWRMEGAWSMSASH
Conjugate
Unconjugated
Target
Alternative Names
TWIST1; twist family bHLH transcription factor 1; CRS; SCS; ACS3; CRS1; BPES2; BPES3; TWIST; bHLHa38; twist-related protein 1; H-twist; twist homolog 1; craniosynostosis; B-HLH DNA binding protein; TWIST homolog of drosophila; class A basic helix-loop-hel
Basic helix-loop-helix (bHLH) transcription factors have been implicated in cell lineage determination and differentiation. The protein encoded by this gene is a bHLH transcription factor and shares similarity with another bHLH transcription factor, Dermo1. The strongest expression of this mRNA is in placental tissue; in adults, mesodermally derived tissues express this mRNA preferentially. Mutations in this gene have been found in patients with Saethre-Chotzen syndrome.
Pathway
Adipogenesis; Neural Crest Differentiation; Proteoglycans in cancer;
Citations
Publication ()
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