TUB (NP_003311, 439 a.a. ~ 538 a.a) partial recombinant protein with GST tag. The sequence is KMSVIVPGMNMVHERVSIRPRNEHETLLARWQNKNTESIIELQNKTPVWNDDTQSYVLNF HGRVTQASVKNFQIIHGNDPDYIVMQFGRVAEDVFTMDYN
This gene encodes a member of the Tubby family of bipartite transcription factors. The encoded protein may play a role in obesity and sensorineural degradation. The crystal structure has been determined for a similar protein in mouse, and it functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis. Two transcript variants encoding distinct isoforms have been identified for this gene.
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