Anti-TSPAN7 (aa 113-212) polyclonal antibody

Species Reactivity

Human

Immunogen

TSPAN7 (NP_004606, 113 a.a. ~ 212 a.a) partial recombinant protein with GST tag. The sequence is RHEIKDTFLRTYTDAMQTYNGNDERSRAVDHVQRSLSCCGVQNYTNWSTSPYFLEHGIPP SCCMNETDCNPQDLHNLTVAATKVNQKGCYDLVTSFMETN

Conjugate

Alternative Names

TSPAN7; tetraspanin 7; A15; MXS1; CD231; MRX58; CCG-B7; TM4SF2; TALLA-1; TM4SF2b; DXS1692E; tetraspanin-7; tspan-7; CD231 antigen; tetraspanin protein; transmembrane protein A15; cell surface glycoprotein A15; transmembrane 4 superfamily 2b; transmembrane

Entrez Gene ID

UniProt ID

Antigen Description

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and may have a role in the control of neurite outgrowth. It is known to complex with integrins. This gene is associated with X-linked mental retardation and neuropsychiatric diseases such as Huntingtons chorea, fragile X syndrome and myotonic dystrophy.

Pathway

Transcriptional misregulation in cancer;