Specifications
Immunogen
A synthetic peptide of human TSPAN7 is used for rabbit immunization.
Target
Alternative Names
TSPAN7; tetraspanin 7; mental retardation, X linked 58 , MRX58, MXS1, TM4SF2, transmembrane 4 superfamily member 2; tetraspanin-7; A15; CD231; DXS1692E; TALLA 1; tspan-7; CD231 antigen; tetraspanin protein; transmembrane protein A15; cell surface glycopro
Product Background
Antigen Description
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and may have a role in the control of neurite outgrowth. It is known to complex with integrins. This gene is associated with X-linked mental retardation and neuropsychiatric diseases such as Huntingtons chorea, fragile X syndrome and myotonic dystrophy.
Pathway
Transcriptional misregulation in cancer, organism-specific biosystem; Transcriptional misregulation in cancer, conserved biosystem;
Citations
Publication ()
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