A synthetic peptide of human TSGA14 is used for rabbit immunization.
Conjugate
Unconjugated
Target
Alternative Names
CEP41; centrosomal protein 41kDa; JBTS15; TSGA14; centrosomal protein of 41 kDa; testis specific, 14; centrosomal protein 41 kDa; testis specific protein A14; testis-specific gene A14 protein;
This gene encodes a centrosomal and microtubule-binding protein which is predicted to have two coiled-coil domains and a rhodanese domain. In human retinal pigment epithelial cells the protein localized to centrioles and cilia. Mutations in this gene have been associated with Joubert Syndrome 15; an autosomal recessive ciliopathy and neurological disorder. Alternative splicing results in multiple transcript variants.
Pathway
Cell Cycle; Cell Cycle, Mitotic; Centrosome maturation; G2/M Transition; Loss of Nlp from mitotic centrosomes; Loss of proteins required for interphase microtubule organization??from the centrosome; Mitotic G2-G2/M phases; Recruitment of mitotic centrosome proteins and complexes; Regulation of PLK1 Activity at G2/M Transition.
Citations
Publication ()
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COA
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