TSG101 recognizes TSG101 protein, the product of a recently identified Tumor Susceptibility Gene whose inactivation in mouse fibroblasts results in cell transformation and the ability of those cells to form tumors in nude mice. The TSG101 gene encodes a 46 kDa protein and contains a proline-rich domain and a luecine-zipper motif within a coiled-coil domain near the carboxyl terminus.
Pathway
Assembly Of The HIV Virion; Budding and maturation of HIV virion; Disease; ESCRT-I complex; Endocytosis; Endosomal Sorting Complex Required For Transport (ESCRT); Glucocorticoid receptor regulatory network; HIV Infection;
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