Anti-TRAIP (aa 370-469) polyclonal antibody

Species Reactivity

Human

Immunogen

TRIP (NP_005870, 370 a.a. ~ 469 a.a) partial recombinant protein with GST tag. The sequence is GQSCAGEPDEELVGAFPIFVRNAILGQKQPKRPRSESSCSKDVVRTGFDGLGGRTKFIQP TDTVMIRPLPVKPKTKVKQRVRVKTVPSLFQAKLDTFLWS

Conjugate

Alternative Names

TRAIP; TRAF interacting protein; TRIP; RNF206; E3 ubiquitin-protein ligase TRAIP; ring finger protein 206; TRAF-interacting protein;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a protein that contains an N-terminal RING finger motif and a putative coiled-coil domain. A similar murine protein interacts with TNFR-associated factor 1 (TRAF1), TNFR-associated factor 2 (TRAF2), and cylindromatosis. The interaction with TRAF2 inhibits TRAF2-mediated nuclear factor kappa-B, subunit 1 activation that is required for cell activation and protection against apoptosis.

Pathway

TNF-alpha/NF-kB Signaling Pathway;