Full length protein corresponding to Human TNFRSF19 aa 1-417. (NP_683760.1)Sequence: MALKVLLEQEKTFFTLLVLLGYLSCKVTCESGDCRQQEFRDRSGNCVPCN QCGPGMELSKECGFGYGEDAQCVTCRLHRFKEDWGFQKCKPCLDCAVVNR FQKANCSATSDAICGDCLPGFYRKTKLVGFQDMECVPCGDPPPPYEPHCA SKVNLVKIASTASSPRD
Conjugate
Unconjugated
Applications
Application Notes
WB: 1 μg/ml.
Target
Alternative Names
TNFRSF19; tumor necrosis factor receptor superfamily, member 19; tumor necrosis factor receptor superfamily member 19; TAJ; TAJ alpha; toxicity and JNK inducer; TRADE; TROY; TAJ-alpha;
TNFRSF19 is a member of the TNF-receptor superfamily. This receptor is highly expressed during embryonic development. It has been shown to interact with TRAF family members, and to activate JNK signaling pathway when overexpressed in cells. This receptor is capable of inducing apoptosis by a caspase-independent mechanism, and it is thought to play an essential role in embryonic development. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Pathway
Cytokine-cytokine receptor interaction;
Citations
Publication ()
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