Anti-TNFRSF12A monoclonal antibody (DCABH-203)

Rabbit Anti-TNFRSF12A monoclonal antibody for WB, IHC, IP Datasheet

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Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Clone
TO31-18
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein
Conjugate
Unconjugated

Applications


Application Notes
Recommended Dilution: WB: 1:500-1:1,000 ; IHC: 1:50-1:200
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Data Examples


Fig1: Western blot analysis of TWEAKR on different lysates using anti-TWEAKR antibody at 1/1,000 dilution. Positive control: Lane 1: NIH/3T3; Lane 2: C2C12
Fig2: Immunohistochemical analysis of paraffin-embedded mouse uterus tissue using anti-TWEAKR antibody. Counter stained with hematoxylin.

Target


Alternative Names
CD 266; CD266; CD266 antigen; FGF inducible 14; FGF-inducible 14; Fibroblast growth factor inducible immediate early response protein 14

Product Background


Antigen Description
Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins. Tumor necrosis factor receptor superfamily member 12A also known as the TWEAK receptor (TWEAKR) is a protein that in humans is encoded by the TNFRSF12A gene. 0The function about TNFRSF12A antigen include protein binding; receptor activity.

Citations


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References


Yaden, BC; Wang, YX; et al. Inhibition of Activin A Ameliorates Skeletal Muscle Injury and Rescues Contractile Properties by Inducing Efficient Remodeling in Female Mice. AMERICAN JOURNAL OF PATHOLOGY 184:1152-1166(2014).
Culp, PA; Choi, D; et al. Antibodies to TWEAK Receptor Inhibit Human Tumor Growth through Dual Mechanisms. CLINICAL CANCER RESEARCH 16:497-508(2010).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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