TNFAIP3 (NP_006281, 691 a.a. ~ 790 a.a) partial recombinant protein with GST tag. The sequence is RTEEQLRSSQRRDVPRTTQSTSRPKCARASCKNILACRSEELCMECQHPNQRMGPGAHRG EPAPEDPPKQRCRAPACDHFGNAKCNGYCNECFQFKQMYG
Conjugate
Unconjugated
Target
Alternative Names
TNFAIP3; tumor necrosis factor, alpha-induced protein 3; A20; OTUD7C; TNFA1P2; tumor necrosis factor alpha-induced protein 3; zinc finger protein A20; TNF alpha-induced protein 3; OTU domain-containing protein 7C; putative DNA-binding protein A20; tumor n
This gene was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). The protein encoded by this gene is a zinc finger protein and ubiqitin-editing enzyme, and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine-mediated immune and inflammatory responses. Several transcript variants encoding the same protein have been found for this gene.
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