Anti-TMED10 polyclonal antibody

Species Reactivity

Human

Immunogen

A synthetic peptide corresponding to human TMED10. The sequence is C-YLRRFFKAKKLIE

Conjugate

Application Notes

ELISA: 1:1000. & The optimal working dilution should be determined by the end user.

Alternative Names

TMED10; transmembrane emp24-like trafficking protein 10 (yeast); p23; TMP21; S31I125; Tmp-21-I; S31III125; P24(DELTA); transmembrane emp24 domain-containing protein 10; p24delta; p24delta1; p24 family protein delta-1; transmembrane protein Tmp21; 21 kDa t

Entrez Gene ID

UniProt ID

Antigen Description

This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complexs gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimers disease. This gene has a pseudogene on chromosome 8.

Pathway

mRNA processing;