Recombinant human TLE1 protein; Source: E. coli derived, PGEX-4T; Tag: GST; Domain: 281-377 aa of BC010100
Conjugate
Unconjugated
Applications
Application Notes
WB: 1:5000-1:50000
General Notes
This product (Catalog No. DPABH-22139) is a rabbit-derived polyclonal antibody raised against human TLE1, targeting the amino acid region 281–377 of the protein. It has been affinity purified by Protein A. TLE1 (Transducin-like enhancer protein 1) is a transcriptional corepressor and binds to a number of transcription factors. It can inhibit NF-kappa-B-regulated gene expression and the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES (PMID: 10660609). TLE1 is highly expressed in postnatal brain (PMID: 29758293; 27852056). DPABH-22139 is suitable for use in Western blot (WB) (1:5,000–1:50,000) application. DPABH-22139 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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