Anti-THOP1 monoclonal antibody (DCABH-4303)

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Clone
FQS8762
Species Reactivity
Mouse, Rat, Human
Immunogen
Synthetic peptide, corresponding to residues in Human Thimet Oligopeptidase (UniProt: P52888).
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/1000 - 1/10000; ICC/IF: 1/100 - 1/250.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
THOP1; thimet oligopeptidase 1; thimet oligopeptidase; endopeptidase 24.15; TOP; MP78
Entrez Gene ID
UniProt ID

Product Background


Pathway
African trypanosomiasis, organism-specific biosystem; African trypanosomiasis, conserved biosystem; Renin-angiotensin system, organism-specific biosystem; Renin-angiotensin system, conserved biosystem;

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References


Krause, DR; Piva, TJ; et al. Characterization and localization of mitochondrial oligopeptidase (MOP) (EC 3.4.24.16) activity in the human cervical adenocarcinoma cell line HeLa. JOURNAL OF CELLULAR BIOCHEMISTRY 66:297-308(1997).
SERIZAWA, A; DANDO, PM; et al. CHARACTERIZATION OF A MITOCHONDRIAL METALLOPEPTIDASE REVEALS NEUROLYSIN AS A HOMOLOG OF THIMET OLIGOPEPTIDASE. JOURNAL OF BIOLOGICAL CHEMISTRY 270:2092-2098(1995).

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