Anti-THOP1 monoclonal antibody (DCABH-847)

Mouse anti-Human THOP1 monoclonal antibody for WB, IHC-P Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG2b
Clone
3E4
Species Reactivity
Human
Immunogen
Recombinant full length Human Thimet Oligopeptidase produced in HEK293T cells (NP_0003240).
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/2000; IHC-P: 1/150;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
THOP1; thimet oligopeptidase 1; thimet oligopeptidase; endopeptidase 24.15; TOP; MP78
Entrez Gene ID
UniProt ID

Product Background


Pathway
African trypanosomiasis, organism-specific biosystem; African trypanosomiasis, conserved biosystem; Renin-angiotensin system, organism-specific biosystem; Renin-angiotensin system, conserved biosystem;

Citations


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References


Miyake, R; Shigeri, Y; et al. Two thimet oligopeptidase-like Pz peptidases produced by a collagen-degrading thermophile, Geobacillus collagenovorans MO-1. JOURNAL OF BACTERIOLOGY 187:4140-4148(2005).
Yamin, R; Malgeri, EG; et al. Metalloendopeptidase EC 3.4.24.15 is necessary for Alzheimer's amyloid-beta peptide degradation. JOURNAL OF BIOLOGICAL CHEMISTRY 274:18777-18784(1999).

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