Rabbit Anti-Human TBC1D15 (a.a. 339-691) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human; Mouse; Rat

Immunogen

Recombinant human TBC1D15 protein; Source: E. coli derived, PET28a; Tag: 6*His; Domain: 339-691 aa of BC028352

Conjugate

Application Notes

WB: 1:500-1:1000
IF/ICC: 1:200-1:800

General Notes

This product (Catalog No. DPABH-18071) is a rabbit-derived polyclonal antibody raised against human TBC1D15, targeting the amino acid region 339–691 of the protein. This antibody exhibits cross-reactivity with Human TBC1D15 from mouse and rat. It has been affinity purified by Protein A. TBC1D15 is a highly conserved protein belonging to the TBC domain family and has similar functions to Rab-GAP. TBC1D15 is ubiquitously expressed and localized predominantly to the cytosol. TBC1D15 is a protein that contains a conserved Tre2/Bub2/Cdc16 (TBC) domain. TBC1D15 can serve as a mitochondrial Rab GTPase-activating protein (Rab-GAP) and influence autophagosome biogenesis and morphology downstream of Parkin activation. TBC1D15 can also control stem cell self-renewal when coupled with the Numb-p53 complex.
DPABH-18071 is suitable for use in Western blot (WB) (1:500–1:1,000), IF/ICC (1:200–1:800) applications.
DPABH-18071 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

TBC1 domain family member 15; Rab7-GAP; Rab7 GAP; GTPase-activating protein RAB7; GTPase activating protein RAB7

Entrez Gene ID

UniProt ID