Anti-TBC1D15 polyclonal antibody (DPAB13663)

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein corresponding to amino acids of human TBC1D15.
Conjugate
Unconjugated

Applications


Application Notes
Immunohistochemistry (1:20-1:50); WB (1:250-1:500) & The optimal working dilution should be determined by the end user.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
RAB7-GAP
Entrez Gene ID
UniProt ID

Product Background


Gene summary
TBC1D15 (TBC1 Domain Family Member 15) is a Protein Coding gene. GO annotations related to this gene include GTPase activator activity. An important paralog of this gene is SGSM2. This gene encodes a member of the Ras-like proteins in brain-GTPase activating protein superfamily that share a conserved Tre-2/Bub2/Cdc16 domain. The encoded protein interacts with Ras-like protein in brain 5A and may function as a regulator of intracellular trafficking. Alternate splicing results in multiple transcript variants.
Antigen Description
Acts as a GTPase activating protein for RAB7A. Does not act on RAB4, RAB5 or RAB6 (By similarity). TBC1 domain family member 15 is a protein that in humans is encoded by the TBC1D15 gene. 0The function about TBC1D15 antigen include Rab GTPase activator activity;protein binding.

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Hodzic, D; Kong, C; et al. TBC1D3, a hominoid oncoprotein, is encoded by a cluster of paralogues located on chromosome 17q12. GENOMICS 88:731-736(2006).

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