This gene belongs to a family of genes that function as receptors for tachykinins. Receptor affinities are specified by variations in the 5-end of the sequence. The receptors belonging to this family are characterized by interactions with G proteins and 7 hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin neurokinin 3, also referred to as neurokinin B.
Pathway
Calcium signaling pathway; Class A/1 (Rhodopsin-like receptors); GPCR downstream signaling; Gastrin-CREB signalling pathway via PKC and MAPK
Citations
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