SUPT4H1 (NP_003159, 18 a.a. ~ 117 a.a) partial recombinant protein with GST tag. The sequence is LCSLVKTIDQFEYDGCDNCDAYLQMKGNREMVYDCTSSSFDGIIAMMSPEDSWVSKWQRV SNFKPGVYAVSVTGRLPQGIVRELKSRGVAYKSRDTAIKT
Conjugate
Unconjugated
Target
Alternative Names
SUPT4H1; suppressor of Ty 4 homolog 1 (S. cerevisiae); SPT4; SPT4H; SUPT4H; transcription elongation factor SPT4; DSIF p14; small hSpt4 subunit; DRB sensitivity-inducing factor 14 kDa subunit;
This gene encodes the small subunit of DRB (5,6-dichloro-1-beta-d-ribofuranosylbenzimidazole) sensitivity-inducing factor (DSIF) complex, which regulates mRNA processing and transcription elongation by RNA polymerase II. The encoded protein is localized to the nucleus and interacts with the large subunit (SUPT5H) to form the DSIF complex. Related pseudogenes have been identified on chromosomes 2 and 12. Alternatively spliced transcript variants have been found for this gene.
Pathway
Abortive elongation of HIV-1 transcript in the absence of Tat; Formation of HIV elongation complex in the absence of HIV Tat; Formation of RNA Pol II elongation complex; Formation of the HIV-1 Early Elongation Complex
Citations
Publication ()
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