Anti-STT3B (aa 492-533) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

antigen sequence: NPPVEDSSDE DDKRNQGNLY DKAGKVRKHA TEQEKTEEGL GP, corresponding to amino acids 492-533 of Human STT3B.

Conjugate

Application Notes

IHC-P: 1/600. ICC/IF: 1 - 4 μg/ml.

Alternative Names

STT3B; STT3B, subunit of the oligosaccharyltransferase complex (catalytic); SIMP; CDG1X; STT3-B; dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B; homolog of yeast STT3; oligosaccharyl transferase subunit STT3B; source of immun

Entrez Gene ID

UniProt ID

Antigen Description

Component of the N-oligosaccharyl transferase enzyme which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). SST3B seems to be involved in complex substrate specificity.

Pathway

N-Glycan biosynthesis; Oligosaccharyltransferase; Protein processing in endoplasmic reticulum;