General Notes
This product (Catalog No. DPABH-18939) is a rabbit-derived polyclonal antibody raised against human STAT5A, targeting the amino acid region 1–794 of the protein. This antibody exhibits cross-reactivity with Human STAT5A from mouse and rat. It has been affinity purified by Protein A. STAT5A (signal transducer and activator of transcription 5A) is a protein-coding gene located on chromosome 17q21.2 in humans, encoding a member of the STAT family of transcription factors that play a central role in cytokine and growth factor signaling pathways. The STAT5A protein is activated through phosphorylation by receptor-associated kinases in response to ligands such as interleukin-2 (IL2), IL3, IL7, granulocyte-macrophage colony-stimulating factor (GM-CSF), erythropoietin, thrombopoietin, and various growth hormones, leading to its dimerization and translocation to the nucleus where it functions as a transcription activator. This gene, also known by aliases such as MGF and STAT5, produces alternatively spliced transcript variants and is broadly expressed across tissues, with highest levels in fat and bone marrow.
DPABH-18939 is suitable for use in ELISA (1:4,000–1:8,000), IHC (1:50–1:100), Western blot (WB) (1:1,000–1:4,000) applications.
DPABH-18939 is supplied as a liquid formulation in 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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