Recombinant fragment corresponding to Human SPC24 aa 119-193.Sequence: ERQEKEVDEDTTVTIPSAVYVAQLYHQVSKIEWDYECEPGMVKGIHHGPS VAQPIHLDSTQLSRKFISDYLWSLV Database link: Q8NBT2
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore.
Pathway
Cell Cycle; M Phase; Mitotic Metaphase and Anaphase; PLK1 signaling events
Citations
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