SPC24 (SPC24, NDC80 kinetochore complex component) is a protein-coding gene. Diseases associated with SPC24 include alzheimer's disease, and among its related super-pathways are Mitotic Anaphase and Mitotic Prometaphase. GO annotations related to this gene include protein binding. Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore.
Pathway
Cell Cycle; Cell Cycle, Mitotic; M Phase; Mitotic Anaphase; Mitotic Metaphase and Anaphase; Mitotic Prometaphase; PLK1 signaling events; Resolution of Sister Chromatid Cohesion; Separation of Sister Chromatids;
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