This gene product belongs to a family of Sp1 related transcription factors, which regulate transcription by binding to consensus GC- and GT-box regulatory elements in target genes. This protein contains a zinc finger DNA-binding domain and several transactivation domains, and has been reported to function as a bifunctional transcription factor that either stimulates or represses transcription of numerous genes. Alternative splicing results in transcript variants encoding different isoforms, and one variant initiates translation from a non-AUG (AUA) codon.
Pathway
PluriNetWork;
Citations
Publication ()
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References
An intramolecular C(sp(3))-H imination using PhI-mCPBA
Herein, a highly exothermic primary amine-polyvalent iodine reaction has been used successfully for selective functionalization of acidic C(sp3)-H groups for a dehydrogenative C-H imination reaction by 4H elimination. Overall, C(sp3)-H imination at 1,5 distances was readily done via organocatalysis using PhI (10 mol%)-mCPBA under ambient conditions.
Acceleration method of fission source convergence based on RMC code
To improve the efficiency of MC criticality calculation, an acceleration method of fission source convergence which gives an improved initial fission source is proposed. In this method, the MC global homogenization is carried out to obtain the macroscopic cross section of each material mesh, and then the nonlinear iterative solution of the SP3 equations is used to determine the fission source distribution. The calculated fission source is very close to the real fission source, which describes its space and energy distribution. This method is an automatic computation process and is tested by the C5G7 benchmark, the results show that this acceleration method is helpful to reduce the inactive cycles and overall running time. (C) 2019 Korean Nuclear Society, Published by Elsevier Korea LLC.