Synthetic peptide: SKVRVLRIDAPEQQ by a Cysteine residue linker, corresponding to C terminal amino acids 426-439 of Human SOCS4 (NP_543143.1; NP_955453.1).
Conjugate
Unconjugated
Applications
Application Notes
ELISA: 1/32000; IHC-P: 3.75 μg/ml.
Target
Alternative Names
SOCS4; suppressor of cytokine signaling 4; SOCS7, suppressor of cytokine signaling 7; SOCS-4; SOCS-7; suppressor of cytokine signaling 7; SH2 domain containing SOCS box protein; SOCS7; DKFZp686J1568;
SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
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