Anti-SLC7A11 polyclonal antibody (DPABH-02066)
Goat Anti-Human SLC7A11 (aa 215-229) polyclonal antibody for ELISA, WB, IHC-P
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Synthetic peptide: KGQTQNFKDAFSGRD by a Cysteine residue linker, corresponding to internal sequence amino acids 215-229 of Human xCT.
ELISA: 1/128000; WB: 0.02 - 0.06 μg/ml; IHC-P: 3.75 μg/ml.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
SLC7A11; solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11; xCT; CCBR1; cystine/glutamate transporter; amino acid transport system xc-
Amino acid transport across the plasma membrane; Cell surface interactions at the vascular wall; SLC-mediated transmembrane transport; Transport of inorganic cations/anions and amino acids/oligopeptides
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Hammad, SM; Twal, WO; et al. Oxidized LDL immune complexes and oxidized LDL differentially affect the expression of genes involved with inflammation and survival in human U937 monocytic cells. ATHEROSCLEROSIS 202:394-404(2009).
Baek, S; Choi, CM; et al. Exploratory Clinical Trial of (4S)-4-(3-[F-18]fluoropropyl)-L-glutamate for Imaging x(C) Transporter Using Positron Emission Tomography in Patients with Non-Small Cell Lung or Breast Cancer. CLINICAL CANCER RESEARCH 18:5427-5437(2012).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.