Anti-SLC7A11 polyclonal antibody (DPABH-02066)

Goat Anti-Human SLC7A11 (aa 215-229) polyclonal antibody for ELISA, WB, IHC-P Datasheet

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Specifications


Host Species
Goat
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
Synthetic peptide: KGQTQNFKDAFSGRD by a Cysteine residue linker, corresponding to internal sequence amino acids 215-229 of Human xCT.
Conjugate
Unconjugated

Applications


Application Notes
ELISA: 1/128000; WB: 0.02 - 0.06 μg/ml; IHC-P: 3.75 μg/ml.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
SLC7A11; solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11; xCT; CCBR1; cystine/glutamate transporter; amino acid transport system xc-
Entrez Gene ID
UniProt ID

Product Background


Pathway
Amino acid transport across the plasma membrane; Cell surface interactions at the vascular wall; SLC-mediated transmembrane transport; Transport of inorganic cations/anions and amino acids/oligopeptides

Citations


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References


Baek, S; Choi, CM; et al. Exploratory Clinical Trial of (4S)-4-(3-[F-18]fluoropropyl)-L-glutamate for Imaging x(C) Transporter Using Positron Emission Tomography in Patients with Non-Small Cell Lung or Breast Cancer. CLINICAL CANCER RESEARCH 18:5427-5437(2012).
Hammad, SM; Twal, WO; et al. Oxidized LDL immune complexes and oxidized LDL differentially affect the expression of genes involved with inflammation and survival in human U937 monocytic cells. ATHEROSCLEROSIS 202:394-404(2009).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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