The SLC6 family of proteins, which includes SLC6A18, acts as specific transporters for neurotransmitters, amino acids, and osmolytes like betaine, taurine, and creatine. SLC6 proteins are sodium cotransporters that derive the energy for solute transport from the electrochemical gradient for sodium ions (Hoglund et al., 2005 [PubMed 16125675]).
Pathway
Amino acid transport across the plasma membrane, organism-specific biosystem; Na+/Cl- dependent neurotransmitter transporters, organism-specific biosystem; SLC-mediated transmembrane transport, organism-specific biosystem; Transmembrane transport of small molecules, organism-specific biosystem; Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds, organism-specific biosystem; Transport of inorganic cations/anions and amino acids/oligopeptides, organ
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
Citations
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Sironen, AI; Uimari, P; et al. Effect of polymorphisms in candidate genes on reproduction traits in Finnish pig populations. JOURNAL OF ANIMAL SCIENCE 88:821-827(2010).
Karunakaran, S; Umapathy, NS; et al. Interaction of tryptophan derivatives with SLC6A14 (ATB(0,+)) reveals the potential of the transporter as a drug target for cancer chemotherapy. BIOCHEMICAL JOURNAL 414:343-355(2008).
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Certificate of Analysis