Specifications
Immunogen
A synthetic peptide of human SLC6A13 is used for rabbit immunization.
Target
Alternative Names
SLC6A13; solute carrier family 6 (neurotransmitter transporter), member 13; GAT2; GAT3; GAT-2; sodium- and chloride-dependent GABA transporter 2; GABA transporter 2; GABA transport protein; solute carrier family 6 (neurotransmitter transporter, GABA), mem
Product Background
Antigen Description
SLC6A13 (solute carrier family 6 (neurotransmitter transporter), member 13) is a protein-coding gene. Diseases associated with SLC6A13 include focal epilepsy, and schizophrenia, and among its related super-pathways are Transmembrane transport of small molecules and Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell. GO annotations related to this gene include neurotransmitter:sodium symporter activity and gamma-aminobutyric acid:sodium symporter activity. An important paralog of this gene is SLC6A6. Sodium-dependent GABA and taurine transporter. In presynaptic terminals, regulates GABA signaling termination through GABA uptake. May also be involved in beta-alanine transport.
Pathway
GABA synthesis, release, reuptake and degradation; GABAergic synapse; GABAergic synapse; Na+/Cl- dependent neurotransmitter transporters; Neuronal System; Neurotransmitter Release Cycle; Reuptake of GABA; SLC-mediated transmembrane transport; Transmembrane transport of small molecules; Transmission across Chemical Synapses; Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds;
Citations
Publication ()
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