Anti-SLC39A8 (C-terminal) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

ZIP8 antibody was raised against a 18 amino acid peptide near the carboxy terminus of human ZIP8.

Conjugate

Alternative Names

SLC39A8; solute carrier family 39 (zinc transporter), member 8; ZIP8; PP3105; BIGM103; LZT-Hs6; zinc transporter ZIP8; ZIP-8; Zrt- and Irt-like protein 8; solute carrier family 39 member 8; LIV-1 subfamily of ZIP zinc transporter 6; BCG induced integral m

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a member of the SLC39 family of solute-carrier genes, which show structural characteristics of zinc transporters. The encoded protein is glycosylated and found in the plasma membrane and mitochondria, and functions in the cellular import of zinc at the onset of inflammation. It is also thought to be the primary transporter of the toxic cation cadmium, which is found in cigarette smoke. Multiple transcript variants encoding different isoforms have been found for this gene. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Oct 2008]

Pathway

Metal ion SLC transporters; SLC-mediated transmembrane transport; Transmembrane transport of small molecules; Transport of glucose and other sugars; Zinc influx into cells by the SLC39 gene family; Zinc transporters