Anti-SLC39A8 monoclonal antibody Made to order

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

A synthetic peptide of human SLC39A8 is used for rabbit immunization.

Conjugate

Alternative Names

SLC39A8; solute carrier family 39 (zinc transporter), member 8; solute carrier family 39 (metal ion transporter), member 8; zinc transporter ZIP8; BIGM103; ZIP-8; Zrt- and Irt-like protein 8; solute carrier family 39 member 8; LIV-1 subfamily of ZIP zinc

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a member of the SLC39 family of solute-carrier genes, which show structural characteristics of zinc transporters. The encoded protein is glycosylated and found in the plasma membrane and mitochondria, and functions in the cellular import of zinc at the onset of inflammation. It is also thought to be the primary transporter of the toxic cation cadmium, which is found in cigarette smoke. Multiple transcript variants encoding different isoforms have been found for this gene. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.

Pathway

Metal ion SLC transporters, organism-specific biosystem; SLC-mediated transmembrane transport, organism-specific biosystem; Transmembrane transport of small molecules, organism-specific biosystem; Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds, organism-specific biosystem; Zinc influx into cells by the SLC39 gene family, organism-specific biosystem; Zinc transporters, organism-specific biosystem;