Specifications
Immunogen
Recombinant fragment corresponding to Human SLC25A17 aa 32-66.Sequence: TARLRLQVDEKRKSKTTHMVLLEIIKEEGLLAPYR Database link: O43808
Applications
Application Notes
IHC-P: 1/50 - 1/200.
Target
Alternative Names
SLC25A17; solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17; solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kD), member 17; peroxisomal membrane protein PMP34; peroxisomal me
Product Background
Antigen Description
Peroxisomal transporter for multiple cofactors like coenzyme A (CoA), flavin adenine dinucleotide (FAD), flavin mononucleotide (FMN) and nucleotide adenosine monophosphate (AMP), and to a lesser extend for nicotinamide adenine dinucleotide (NAD(+)), adenosine diphosphate (ADP) and adenosine 3,5-diphosphate (PAP). May catalyze the transport of free CoA, FAD and NAD(+) from the cytosol into the peroxisomal matrix by a counter-exchange mechanism. Inhibited by pyridoxal 5-phosphate and bathophenanthroline in vitro.
Pathway
Alpha-oxidation of phytanate; Metabolism; Metabolism of lipids and lipoproteins; Peroxisomal lipid metabolism; Peroxisome;
Citations
Publication ()
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