Anti-SLC22A18 monoclonal antibody Made to order

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

A synthetic peptide of human SLC22A18 is used for rabbit immunization.

Conjugate

Alternative Names

SLC22A18; solute carrier family 22, member 18; BWSCR1A, IMPT1, ORCTL2, SLC22A1L, solute carrier family 22 (organic cation transporter), member 1 like; solute carrier family 22 member 18; BWR1A; ITM; TSSC5; ORCTL-2; efflux transporter-like protein; p45 Bec

Entrez Gene ID

UniProt ID

Antigen Description

This gene is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region as well as the transport of chloroquine- and quinidine-related compounds in the kidney. Two alternative transcripts encoding the same isoform have been described.

Pathway

Organic cation transport, organism-specific biosystem; Organic cation/anion/zwitterion transport, organism-specific biosystem; SLC-mediated transmembrane transport, organism-specific biosystem; Transmembrane transport of small molecules, organism-specific biosystem; Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds, organism-specific biosystem;