Anti-SLC1A2 monoclonal antibody (CAB-8191MH)

Mouse anti-Human SLC1A2 monoclonal antibody for ELISA, WB Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG2a
Clone
296DU58.7.2
Species Reactivity
Human, Mouse
Immunogen
SLC1A2 (NP_004162, 160 a.a.~240 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Unconjugated

Applications


Application Notes
WB: 1:500-4000
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
SLC1A2; solute carrier family 1 (glial high affinity glutamate transporter), member 2; excitatory amino acid transporter 2; EAAT2; GLT 1; glutamate/aspartate transporter II
Entrez Gene ID
UniProt ID

Product Background


Pathway
Amyotrophic lateral sclerosis (ALS), organism-specific biosystem; Amyotrophic lateral sclerosis (ALS), conserved biosystem; Astrocytic Glutamate-Glutamine Uptake And Metabolism, organism-specific biosystem; Glutamatergic synapse, organism-specific biosystem; Glutamatergic synapse, conserved biosystem; Neuronal System, organism-specific biosystem; Neurotransmitter uptake and Metabolism In Glial Cells, organism-specific biosystem;

Citations


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References


Bjornsen, LP; Hadera, MG; et al. The GLT-1 (EAAT2; slc1a2) glutamate transporter is essential for glutamate homeostasis in the neocortex of the mouse. JOURNAL OF NEUROCHEMISTRY 128:641-649(2014).
Holmseth, S; Scott, HA; et al. THE CONCENTRATIONS AND DISTRIBUTIONS OF THREE C-TERMINAL VARIANTS OF THE GLT1 (EAAT2; slc1a2) GLUTAMATE TRANSPORTER PROTEIN IN RAT BRAIN TISSUE SUGGEST DIFFERENTIAL REGULATION. NEUROSCIENCE 162:1055-1071(2009).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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