Anti-SKAP1 (aa 1-100) polyclonal antibody

Species Reactivity

Human

Immunogen

SCAP1 (NP_003717, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. The sequence is MQAAALPEEIRWLLEDAEEFLAEGLRNENLSAVARDHRDHILRGFQQIKARYYWDFQPQG GDIGQDSSDDNHSGTLGLSLTSDAPFLSDYQDEGMEDIVK

Conjugate

Alternative Names

SKAP1; src kinase associated phosphoprotein 1; SCAP1; SKAP55; HEL-S-81p; src kinase-associated phosphoprotein 1; pp55; SKAP-55; src family associated phosphoprotein 1; src family-associated phosphoprotein 1; src kinase-associated phosphoprotein of 55 kDa;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a T cell adaptor protein, a class of intracellular molecules with modular domains capable of recruiting additional proteins but that exhibit no intrinsic enzymatic activity. The encoded protein contains a unique N-terminal region followed by a PH domain and C-terminal SH3 domain. Along with the adhesion and degranulation-promoting adaptor protein, the encoded protein plays a critical role in inside-out signaling by coupling T-cell antigen receptor stimulation to the activation of integrins.

Pathway

Rap1 signaling pathway; TCR Signaling Pathway;