Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human SKAP55 aa 50-150 (Cysteine residue). The exact sequence is proprietary.Database link: Q86WV1
Positively regulates T-cell receptor signaling by enhancing the MAP kinase pathway. Required for optimal conjugation between T-cells and antigen-presenting cells by promoting the clustering of integrin ITGAL on the surface of T-cells. May be involved in high affinity immunoglobulin epsilon receptor signaling in mast cells.
Pathway
T Cell Receptor Signaling Pathway, organism-specific biosystem;
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