Anti-SIRT6 monoclonal antibody (DCABH-852)
Mouse anti-Human SIRT6 monoclonal antibody for WB, ICC/IF
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Recombinant fragment, corresponding to amino acids 88-352 of Human SIRT6 produced in E.coli (NP_057623).
WB: 1/500 - 1/2000; ICC/IF: 1/100;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
SIRT6; sirtuin 6; sirtuin (silent mating type information regulation 2 homolog) 6 (S. cerevisiae) , sirtuin (silent mating type information regulation 2, S. cerevisiae, homolog) 6; NAD-dependent deacetylase sirtuin-6; sirtuin type 6; SIR2-like protein 6
Signaling events mediated by HDAC Class I, organism-specific biosystem;
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Cardus, A; Uryga, AK; et al. SIRT6 protects human endothelial cells from DNA damage, telomere dysfunction, and senescence. CARDIOVASCULAR RESEARCH 97:571-579(2013).
Liszt, G; Ford, E; et al. Mouse Sir2 homolog SIRT6 is a nuclear ADP-ribosyltransferase. JOURNAL OF BIOLOGICAL CHEMISTRY 280:21313-21320(2005).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.