Anti-SIRT6 monoclonal antibody (DCABH-852)

Mouse anti-Human SIRT6 monoclonal antibody for WB, ICC/IF Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
2H4
Species Reactivity
Human
Immunogen
Recombinant fragment, corresponding to amino acids 88-352 of Human SIRT6 produced in E.coli (NP_057623).
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/500 - 1/2000; ICC/IF: 1/100;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
SIRT6; sirtuin 6; sirtuin (silent mating type information regulation 2 homolog) 6 (S. cerevisiae) , sirtuin (silent mating type information regulation 2, S. cerevisiae, homolog) 6; NAD-dependent deacetylase sirtuin-6; sirtuin type 6; SIR2-like protein 6
Entrez Gene ID
UniProt ID

Product Background


Pathway
Signaling events mediated by HDAC Class I, organism-specific biosystem;

Citations


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References


Cen, YN; Falco, JN; et al. Mechanism-based affinity capture of sirtuins. ORGANIC & BIOMOLECULAR CHEMISTRY 9:987-993(2011).
Yao, QP; Zhang, P; et al. The role of SIRT6 in the differentiation of vascular smooth muscle cells in response to cyclic strain. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY 49:98-104(2014).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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