Anti-SIRT2 monoclonal antibody (DCABH-2976) Knockout Validated

Rabbit anti-Human SIRT2 monoclonal antibody for WB

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Clone
FQS2778
Species Reactivity
Rat, Human
Immunogen
Synthetic peptide corresponding to residues on the N terminus of Human SIRT2 (UniProt Q8IXJ6).
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/500 - 1/1000;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
SIRT2; sirtuin 2; SIR2L, sirtuin (silent mating type information regulation 2 homolog) 2 (S. cerevisiae) , sirtuin (silent mating type information regulation 2, S.cerevisiae, homolog) 2; NAD-dependent deacetylase sirtuin-2; sirtuin type 2; SIR2-like pro
Entrez Gene ID
UniProt ID

Product Background


Pathway
Signaling events mediated by HDAC Class I, organism-specific biosystem; Signaling events mediated by HDAC Class III, organism-specific biosystem;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Imaoka, N; Hiratsuka, M; et al. Prognostic significance of sirtuin 2 protein nuclear localization in glioma: An immunohistochemical study. ONCOLOGY REPORTS 28:923-930(2012).
Cen, YN; Falco, JN; et al. Mechanism-based affinity capture of sirtuins. ORGANIC & BIOMOLECULAR CHEMISTRY 9:987-993(2011).

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