Synthetic peptide corresponding to residues on the N terminus of Human SIRT2 (UniProt Q8IXJ6).
Conjugate
Unconjugated
Applications
Application Notes
WB: 1/500 - 1/1000;
Target
Alternative Names
SIRT2; sirtuin 2; SIR2L, sirtuin (silent mating type information regulation 2 homolog) 2 (S. cerevisiae) , sirtuin (silent mating type information regulation 2, S.cerevisiae, homolog) 2; NAD-dependent deacetylase sirtuin-2; sirtuin type 2; SIR2-like pro
NAD-dependent protein deacetylase, which deacetylates the Lys-40 of alpha-tubulin. Involved in the control of mitotic exit in the cell cycle, probably via its role in the regulation of cytoskeleton.
Pathway
Signaling events mediated by HDAC Class I, organism-specific biosystem; Signaling events mediated by HDAC Class III, organism-specific biosystem;
Citations
Publication ()
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