Synthetic peptide corresponding to residues on the N terminus of Human SIRT2 (UniProt Q8IXJ6).
Conjugate
Unconjugated
Applications
Application Notes
WB: 1/500 - 1/1000;
Target
Alternative Names
SIRT2; sirtuin 2; SIR2L, sirtuin (silent mating type information regulation 2 homolog) 2 (S. cerevisiae) , sirtuin (silent mating type information regulation 2, S.cerevisiae, homolog) 2; NAD-dependent deacetylase sirtuin-2; sirtuin type 2; SIR2-like pro
NAD-dependent protein deacetylase, which deacetylates the Lys-40 of alpha-tubulin. Involved in the control of mitotic exit in the cell cycle, probably via its role in the regulation of cytoskeleton.
Pathway
Signaling events mediated by HDAC Class I, organism-specific biosystem; Signaling events mediated by HDAC Class III, organism-specific biosystem;
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
Citations
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Orellana, ME; Quezada, C; et al. Expression of SIRT2 and SIRT6 in Retinoblastoma. OPHTHALMIC RESEARCH 53:100-108(2015).
Werner, HB; Kuhlmann, K; et al. Proteolipid protein is required for transport of sirtuin 2 into CNS myelin. JOURNAL OF NEUROSCIENCE 27:7717-7730(2007).
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COA
Certificate of Analysis
