Recombinant fragment corresponding to Human mSin3A aa 1-120 (N terminal).Sequence: MKRRLDDQESPVYAAQQRRIPGSTEAFPHQHRVLAPAPPVYEAVSETMQS ATGIQYSVTPSYQVSAMPQSSGSHGPAIAAVHSSHHHPTAVQPHGGQVVQ SHAHPAPPVAPVQGQQQFQR Database link: Q96ST3
Conjugate
Unconjugated
Applications
Application Notes
WB: 1/500 - 1/2000; IHC-P: 1/50 - 1/200;
Target
Alternative Names
SIN3A; SIN3 transcription regulator family member A; paired amphipathic helix protein Sin3a; transcriptional regulator, SIN3A; transcriptional corepressor Sin3a; transcriptional co-repressor Sin3A; SIN3 transcription regulator homolog A; SIN3 homolog A, t
Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3A to DNA. Acts as a corepressor for REST.
Pathway
C-MYB transcription factor network; EGFR1 Signaling Pathway; Factors involved in megakaryocyte development and platelet production; Gene Expression
Citations
Publication ()
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COA
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