Anti-SIGLEC1 monoclonal antibody (DCABY-496)

Mouse anti-Rat SIGLEC1 monoclonal antibody for IHC-Fr, FC, IF, IP Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG2a
Clone
FE4
Species Reactivity
Rat
Immunogen
Rat Spleen cell homogenate
Conjugate
Unconjugated

Applications


Application Notes
Flow Cyt: 1/500; Immunohistology - Frozen: 1/50 - 1/250
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
SIGLEC1; sialic acid binding Ig-like lectin 1, sialoadhesin; Sn; sialoadhesin
Entrez Gene ID
UniProt ID

Product Background


Pathway
Adaptive Immune System; Allograft rejection; Autoimmune thyroid disease; CD28 co-stimulation; CD28 dependent PI3K/Akt signaling; CD28 dependent Vav1 pathway; CTLA4 inhibitory signaling; Cell adhesion molecules (CAMs); Constitutive PI3K/AKT Signaling in Cancer; Costimulation by the CD28 family; DAP12 interactions; DAP12 signaling; Disease; Downstream Signaling Events Of B Cell Receptor (BCR); Downstream signal transduction; Downstream signaling of activated FGFR; Fc epsilon receptor (FCERI) signa

Citations


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References


Malhotra, S; Bustamante, MF; et al. Search for Specific Biomarkers of IFN beta Bioactivity in Patients with Multiple Sclerosis. PLOS ONE 6:-(2011).
Satoh, J; Tabunoki, H; et al. Immunohistochemical characterization of microglia in Nasu-Hakola disease brains. NEUROPATHOLOGY 31:363-375(2011).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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