Anti-SIGIRR monoclonal antibody (DMABT-H37191)

Rat anti-Mouse SIGIRR monoclonal antibody for WB Datasheet

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Host Species
Species Reactivity


Alternative Names
SIGIRR; single immunoglobulin and toll-interleukin 1 receptor (TIR) domain; single Ig IL-1-related receptor; toll/interleukin-1 receptor 8; single Ig IL-1R-related protein; single Ig IL-1R-related molecule
Entrez Gene ID
UniProt ID

Product Background

Antigen Description
Single Ig IL-1-related receptor is a protein that in humans is encoded by the SIGIRR gene. 0The function about SIGIRR antigen include receptor activity; transmembrane signaling receptor activity.


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Drexler, SK; Kong, P; et al. SIGIRR/TIR-8 Is an Inhibitor of Toll-like Receptor Signaling in Primary Human Cells and Regulates Inflammation in Models of Rheumatoid Arthritis. ARTHRITIS AND RHEUMATISM 62:2249-2261(2010).
Riva, F; Rahman, MM; et al. TIR8 receptor expression in bovine tissues. VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY 136:65-70(2010).

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